There is no such thing as spiritual mastery, and your pursuit of it only puts you at odds with the human experience you’re supposed to have. Too many of us hinge our lives on things happening that overwhelm our beliefs and security and shock our senses, then complain that life is too much (take the constant blather of how awful the year (current year) has been, for example).
Nothing goes “wrong” in human experience except for your idea of how it’s supposed to be, and that “idea” is the foundation of all spiritual ideology and the source of frustrating pursuits that never yield the “mastery” you seek.
Mastery of life is living this moment without conflict with what you think it should look like. In other words, don’t be at odds with what is happening or with those who think “what is happening” is what should or shouldn’t be happening. They’re as nutty as you are! Love nuts and enjoy each moment with them. Doing so will never be “mastery,” but it will be spiritual.